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Prospective assessment of the impact of endometriomas and their removal on ovarian reserve and determinants of the rate of decline in ovarian reserve

Yazarlar : Gurkan Uncu, Isil Kasapoglu, Kemal Ozerkan, Ayse Seyhan, Arzu Oral Yilmaztepe, Baris Ata
Yayın tarihi : 2013/8/1
Dergi : Human reproduction
Cilt : 28
Sayı :8
Sayfalar : 2140-2145
Yayıncı : Oxford University Press

Should asymptomatic bacteriuria be screened in pregnancy?

Yazarlar : Y Uncu, G Uncu, A Esmer, N Bilgel
Yayın tarihi : 2002/1/1
Dergi : Clinical and experimental obstetrics & gynecology
Cilt : 29
Sayı : 4
Sayfalar : 281-285

The incidence of asymptomatic bacteriuria is reported as 2-14% during pregnancy. Fetal and maternal complications like acute pyelonephritis, hypertension, anemia, preterm labor, low-birth-weight infants and intrauterine growth retardation can be expected. The purpose of this study was to determine the incidence of asymptomatic bacteriuria during pregnancy and its relation to pregnancy complications. The study involved 270 pregnant women up to 32 gestational weeks during a 9-month period. At the initial visit, they were screened with urine culture in order to detect asymptomatic bacteriuria. A control group was formed in a retrospective manner from the first day of the study with 186 pregnant women who delivered in our clinic and who were not screened for asymptomatic bacteriuria. The incidence of asymptomatic bacteriuria was 9.31%. Escherichia coli accounted for 79%, which was the most frequent of the isolates. We observed recurrence and had to apply treatment again to 21.7% of the women. The sensitivity, specificity, positive predictive and negative predictive values of leucocyturia as a screening test for asymptomatic bacteriuria were 91.3%, 83.6%, 45.6% and 98.5%, respectively. We diagnosed preterm labor in six of 23 (26%) with asymptomatic bacteriuria and 16 in 163 (9.3%) women in the urine culture negative group. The ratio acute pyelonephritis in the group which was routinely screened and treated for asymtomatic bacteriuria was 0.5% while the prevalence was 2.1% in the nonscreened group. Considering the relatively high incidence of asymptomatic bacteriuria during pregnancy and the relevant complications, we propose …

Endometrioma-related reduction in ovarian reserve (ERROR): a prospective longitudinal study

Yazarlar : Isil Kasapoglu, Baris Ata, Ozlem Uyaniklar, Ayse Seyhan, Adnan Orhan, Sule Yildiz Oguz, Gurkan Uncu
Yayın tarihi : 2018/7/1
Dergi : Fertility and sterility
Cilt : 110
Sayı : 1
Sayfalar : 122-127
Yayıncı : Elsevier
Objective
To evaluate whether endometrioma is associated with a progressive decline in ovarian reserve, and to compare the rate of decline with natural decline in ovarian reserve.

Design
Prospective, observational study.

Setting
Tertiary university hospital, endometriosis clinic.

Patient(s)
Forty women with endometrioma and 40 age-matched healthy controls.

Intervention(s)
Women with endometriomas who did not need hormonal/surgical treatment at the time of recruitment and were expectantly managed. Controls were age-matched, healthy women. All participants underwent serum antimüllerian hormone (AMH) testing twice, 6 months apart. Sexually active patients with endometrioma also underwent antral follicle count.

Main Outcome Measure(s)
Change in serum AMH levels.

Result(s)
Median (25th–75th percentile) serum AMH level at recruitment was 2.83 (0.70–4.96) ng/mL in the endometrioma group and 4.42 (2.26 …